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This article is intended for qualified aesthetic practitioners in the UK. It is not advice for members of the public.
Neauvia is an aesthetics company whose injectable range is built around hyaluronic acid crosslinked with polyethylene glycol (PEG) rather than the more familiar BDDE. For a practitioner the practical question is simpler than the chemistry: which Neauvia product goes where, at what depth, and how does each one fit alongside the rest of your toolkit? This article maps the range product by product, using the manufacturer's own stated concentrations and injection planes, and adds the planning points that tend to get lost on a product sheet.
Most HA fillers on the UK market are crosslinked with 1,4-butanediol diglycidyl ether (BDDE). Neauvia describes its crosslinked products as "pegylated dermal fillers", meaning the HA network is crosslinked using a PEG-based agent. Two further features run through almost the whole range:
Neauvia states that its fillers are Class III medical devices regulated under the EU MDR 2017/745, and the crosslinked products carry a manufacturer-stated "6 months degradation average time" on their product pages (Neauvia, Intense product page). Treat that as the manufacturer's figure rather than a longevity promise to a patient; clinical duration varies with area, mobility, volume and individual metabolism.
The summaries below use the HA concentrations and injection planes stated on Neauvia's own product pages. Always confirm against the instructions for use (IFU) packed with the batch you are injecting, as specifications can change between markets and revisions.
Hydro Deluxe is the outlier in the range. It is a non-crosslinked HA hydrogel at 18 mg/ml, enriched with CaHA, glycine and L-proline, and indicated for injection into the dermis and epidermis of the face and neck (Neauvia, Hydro Deluxe). In practice it sits with skin boosters and mesotherapy rather than with volumising fillers. The Neauvia Organic Hydro Deluxe 2 x 2.5ml product information recommends a course of four treatments at three-week intervals, with a maintenance session around six months later.
Typical candidates are patients with dehydrated, crepey or dull skin who do not need structural support. Because it is non-crosslinked and low-viscosity, it suits micro-papule or micro-bolus delivery across the face, neck and décolletage, and some practitioners deliver it by cannula in fanning passes to reduce entry points. A comparison practitioners often search for is Hydro Deluxe versus Profhilo. They are different products with different protocols, so the comparison is best made on indication, protocol length and patient preference for number of visits rather than on brand.
Intense Lips is a crosslinked PEG-HA at 24 mg/ml with glycine and L-proline, indicated for the vermilion and perioral area (Neauvia, Intense Lips). The manufacturer rates its injection profile as "medium". It does not list lidocaine among its ingredients, which matters for your comfort planning: you will need a topical anaesthetic or a nerve block strategy that sits within your own competence and prescribing arrangements.
The Neauvia Organic Intense Lips 1ml works for definition, border work and modest volume. For patients after significant projection, layering it over a firmer product is not usually necessary; a conservative first session with a review at two weeks gives you a clearer read on how the gel settles in that individual.
These three share the same amino acid base but differ in concentration and stated plane:
The UK site also lists Intense Man, Intense Rheology and Intense Rose (Neauvia UK, fillers range). Intense Man is formulated with male tissue in mind, which is useful when you want stronger support along the jawline and chin without moving to a different brand.
Stimulate is the most distinctive product in the range. It combines crosslinked PEG-HA at 26 mg/ml with CaHA, glycine and L-proline, and is indicated for the subdermis and/or over the periosteum of the face, with a "medium/high" injection profile (Neauvia, Stimulate). The idea is immediate HA volume plus the collagen-stimulating rationale associated with CaHA.
Clinically, that dual nature should shape where you use it. It makes sense in areas of volume loss where tissue quality is also poor, such as the lateral cheek, pre-jowl sulcus or temples in experienced hands. It is a less natural choice for the lips, the tear trough or very thin skin, where any particulate component adds risk of visibility and where full reversibility matters more. You can view the Neauvia Organic Stimulate 1ml product details for the full composition.
The fastest way to use the range well is to plan by plane, not by area name. A rough working map:
Neauvia promotes what it calls Smart Combination Therapy, pairing injectables with devices and topical skincare. Whatever your view of branded protocols, the principle of treating structure and skin quality as separate problems is sound. A common sequence is structural support first with Intense or Stimulate, followed by a course of Hydro Deluxe once the filler has settled. If you combine injectables with energy-based devices on the same day, check the IFU and the device manufacturer's guidance on timing and order rather than relying on general claims about heat resistance.
Neauvia's product pages do not state needle gauges, so use the needles supplied in the box and the IFU. For deeper volumising products, many practitioners favour a blunt-tip cannula in the midface and pre-jowl area to reduce the number of entry points and the risk of intravascular placement, while using a needle for supraperiosteal boluses where precise placement on bone is the goal. Our Neauvia Organic collection lists the current range alongside stock levels.
The fundamentals do not change because the crosslinker does. Know the anatomy of every danger zone you inject, aspirate where it is meaningful but do not rely on it, inject slowly with low pressure, and keep an emergency protocol and the necessary prescription-only medicines available through an appropriate prescriber.
Two points are specific to this range. First, check the IFU for how each product is expected to respond to hyaluronidase before you use it, and plan your occlusion response accordingly; products containing CaHA, such as Stimulate, include a component that hyaluronidase does not dissolve. Second, document batch numbers and the exact product used, because the range has several similarly named references and accurate records matter if you need to report an adverse incident to the MHRA Yellow Card scheme.
Neauvia's crosslinked fillers are hyaluronic acid hydrogels crosslinked with a PEG-based agent and enriched with glycine and L-proline. Stimulate and Hydro Deluxe also contain calcium hydroxyapatite. Hydro Deluxe is non-crosslinked.
Intense is a 28 mg/ml product indicated for the subcutis and/or supraperiosteal plane, so it suits deep folds, cheek and chin support and facial contouring rather than superficial lines or lips.
Suitability depends on the patient, the area and your experience with the product. Neauvia states that its fillers are Class III devices under EU MDR. As with any brand, buy only from a legitimate UK supplier, read the IFU and build your own experience with conservative volumes and structured reviews.
Both are used for skin quality rather than volume, but they have different compositions and protocols. Hydro Deluxe is an 18 mg/ml non-crosslinked HA with CaHA and amino acids, typically given as a course of four sessions. Choose based on indication, the number of visits the patient can commit to and your familiarity with each technique.
The ingredient lists on Neauvia's product pages for Intense, Intense Lips, Stimulate and Hydro Deluxe do not include lidocaine, so plan patient comfort separately.
The Neauvia range is easiest to use when you stop thinking of it as one brand and start treating it as a set of planes: Hydro Deluxe for the skin, Intense Flux and LV for soft volume, Intense Lips for the lips, and Intense or Stimulate for deep support. Read each IFU, start conservatively, and keep your complication protocol and records as rigorous as you would with any other filler.
