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This article is written for qualified aesthetic practitioners (doctors, dentists, nurse and pharmacist prescribers, and other appropriately trained clinicians). It is not advice for members of the public.
Teosyal filler is the hyaluronic acid (HA) range made by Teoxane, the Swiss laboratory that Valérie Taupin founded in Geneva in 2003. In UK clinics it splits into two families: the RHA line, built for areas that move a lot, and the older PureSense line, which includes Redensity 1 and Redensity 2, two of the best-known products in the category. To choose well, you need to know which family a product belongs to and what each gel is designed to do, not just which syringe sold best last month.
This guide works through the range product by product, explains what the RHA manufacturing process changes, and covers how practitioners usually fit Teosyal alongside the other HA brands they stock.
Most HA fillers are made the same way. Long hyaluronic acid chains are cross-linked with BDDE (1,4-butanediol diglycidyl ether) to slow degradation, and the resulting gel is sized and sterilised. Brands differ mainly in how they handle that cross-linking step and in how much HA and cross-linker they use.
Teoxane calls its RHA line "Resilient Hyaluronic Acid". It is made with a process the company calls Preserved Network Technology (PNT), which Teoxane describes as a heatless process. According to the manufacturer, PNT "preserves the dynamic long chains of HA naturally found in our skin and requires minimal cross-linking to achieve desired filler properties" (Teoxane, HCP product page).
In clinic, this is meant to give a gel that stretches and recovers as the face moves, instead of a stiff bolus that shows when the patient smiles or talks. That is why every RHA indication on Teoxane's own literature is written around dynamic lines and areas. The supporting trial work includes Rzany et al. (Dermatologic Surgery, 2019), which tested three RHA fillers "crosslinked with decreased BDDE" for dynamic wrinkles.
There is also a regulatory reference point. The US FDA's summary of safety and effectiveness data records that RHA 2, RHA 3 and RHA 4 were first approved in October 2017. It describes the gels as 23 mg/g sodium hyaluronate cross-linked with BDDE, with the degree of cross-linking rising from RHA 2 to RHA 4. US-market versions now use mepivacaine. UK stock is supplied in its CE-marked form, so always read the instructions for use (IFU) of the exact product you hold rather than relying on US labelling.
PureSense is Teoxane's earlier generation of gels, which predates the RHA line. It is still widely used in UK clinics, largely because of two products, Redensity 1 and Redensity 2, which are covered in their own section below.
Teoxane's indication headlines are short. The notes below follow them and add the practical context most injectors apply.
The softest gel in the line, labelled for "dynamic superficial wrinkles". Practitioners use it for fine perioral lines, superficial lines on the cheek, and lines that only appear with expression. It is placed superficially, and many injectors use a fine needle with a careful linear threading or micro-droplet technique to avoid visible product.
Labelled for "dynamic moderate wrinkles & lips". It suits moderate nasolabial folds and marionette lines, and lips where the patient wants soft hydration and definition more than volume. It is placed in the mid-dermis.
Firmer than RHA 2, labelled for "dynamic severe wrinkles and lips". It works for deeper folds and for lip volume in patients with good tissue support. Many injectors prefer it for the body of the lip and keep RHA 2 for the vermilion border.
The most cross-linked RHA gel, supplied in 1.2 ml syringes. It is labelled for "volume in dynamic extended areas". In practice it is used for midface volume, the lateral cheek and the jawline, where the gel needs to support tissue but still move with chewing and smiling. Placement depth depends on the area and technique, so check the IFU for the exact product. Teosyal RHA 4 (2x1.2ml) is one of the products we are asked about most for jawline and cheek work.
A lip-specific RHA product labelled for "subtle volume and contour". It is aimed at first-time lip patients or anyone who wants definition without obvious size change. Teosyal RHA Kiss Lidocaine (2x0.7ml) comes in smaller syringes, which makes it practical for conservative top-ups.
Redensity 1 is a skin booster, not a volumiser. Teoxane positions it for "skin redensification and prevention of signs of ageing". It combines HA with what the company calls its Dermo-Restructuring Complex of amino acids, antioxidants and vitamins. It is delivered as micro-injections across the face, neck or décolletage, usually as a course of sessions.
Teoxane's summary of the SKINQARE study, published in the Aesthetic Surgery Journal, describes RHA 1 followed by Redensity 1 as a sequential protocol for skin quality. The company reports that adding Redensity 1 extended improvements in hydration and elasticity for up to five months compared with RHA 1 alone. Read the published paper before you build a protocol around it, because the manufacturer's summary is not the full dataset.
Teoxane describes Teosyal Redensity II PureSense as the "first and only hyaluronic acid gel designed for under eye hollows". Because it is purpose-built for a thin-skinned area where swelling and the Tyndall effect are the usual concerns, follow the IFU closely on depth, volume and technique. Patient selection matters more than product choice in this area. For a fuller comparison of tear trough options, see our guide to the best filler for tear trough.
PureSense Ultra Deep is the firm volumiser of the older line, labelled for "volume in targeted areas", with a stated design focus on lift and projection. It is used for chin, malar and temple support in deep planes. PureSense Kiss is the original lip product. You will also see Deep Lines and Global Action from earlier PureSense generations. Many clinics have since moved those indications over to RHA 2 and RHA 3, but some injectors still like how they handle.
Few clinics stock a single brand. Teosyal usually earns its place for one of three reasons.
Against Juvederm or Restylane, the useful comparison is gel behaviour rather than brand name: G-prime, cohesivity, how the product spreads under pressure and how it feels through your chosen needle or cannula. Our Juvederm range guide covers the equivalent Allergan products if you want to map one range against the other.
Read the IFU for the exact SKU. Several Teosyal products are sold with and without lidocaine, in different syringe sizes, and with different supplied needles. The approved injection depth and maximum volumes are in the leaflet, not in a training-day handout.
Plan around movement. Because RHA gels are meant to move with the face, assess patients in animation as well as at rest, both when planning and at review. A product that looks right in repose but feels stiff when the patient smiles is the problem the range is designed to avoid.
Keep complication readiness standard. Teosyal products are HA and can be degraded with hyaluronidase. Your vascular occlusion protocol, emergency kit and prescriber access should be the same whatever brand you use. Follow current Aesthetic Complications Expert (ACE) Group guidance and your own clinic policy.
Storage and traceability. Store in line with the manufacturer's temperature range, keep the batch stickers in the patient record, and buy only through a supply chain you can document. That matters for insurance and for any future product query.
You can browse the full range, including RHA, PureSense and Redensity, on our Teosyal collection page.
Teoxane is the Swiss company. Teosyal is the brand name of its injectable HA range. You will see both names on packaging and in supplier catalogues.
RHA products are made with Teoxane's Preserved Network Technology and are positioned for dynamic areas. PureSense is the earlier line and includes Redensity 1, Redensity 2, Ultra Deep and Kiss.
Neither brand is better across the board. They use different manufacturing approaches and have different gel properties. The right choice depends on the area, the tissue, your technique and the result the patient wants. Many clinics stock both.
Duration depends on the product, area, volume, technique and patient factors such as metabolism and how much the area moves. Use the duration data in each product's IFU and the relevant clinical studies when you consent patients, and avoid quoting a single figure for the whole range.
Teoxane designed and labelled Redensity 2 for under-eye hollows. Using it elsewhere would be off-label. That decision rests with the prescriber and should be documented and discussed with the patient.
Teosyal filler gives practitioners two distinct toolkits. RHA covers dynamic lines and volume in areas that move, and PureSense provides dedicated products for the tear trough and skin quality. If you learn the indications for each SKU and assess patients in animation, the range is straightforward to integrate alongside the other HA brands you already use.
